;PMID: 1384545 ;source_file_1767.mrg ;Release 0.9 of PennBioIE ;Funded by NSF ITR EIA-0205448 ;0)section:[e:0..66] = [t:0..66] ;1)sentence:[e:72..187] = [t:72..187] ;2)section:[e:191..211] = [t:191..211] ;3)section:[e:215..264] = [t:215..264] ;4)section:[e:268..300] = [t:268..300] ;5)sentence:[e:304..667] = [t:304..667] ;6)sentence:[e:668..787] = [t:668..787] ;7)section:[e:791..835] = [t:791..835] ;section 0 Span:0..66 ;Zhongguo Zhong Yao Za Zhi. 1992 Apr;17(4):233-6, inside backcover. (SEC (FRAG (NNP:[0..8] Zhongguo) (NNP:[9..14] Zhong) (NNP:[15..18] Yao) (NNP:[19..21] Za) (NNP:[22..25] Zhi) (.:[25..26] .) (CD:[27..31] 1992) (.:[32..39] Apr;17-LRB-) (CD:[39..40] 4) (-RRB-:[40..41] -RRB-) (::[41..42] :) (CD:[42..45] 233) (JJ:[45..47] -6) (,:[47..48] ,) (IN:[49..55] inside) (RB:[56..65] backcover) (.:[65..66] .))) ;sentence 1 Span:72..187 ;[Mechanisms of protective action of radix Salviae miltiorrhizae (RSM) against ; experimental hepatic injury in rats] ;[108..135]:substance:"radix Salviae miltiorrhizae" ;[137..140]:substance:"RSM" (SENT (NP-HLN (-LRB-:[72..73] -LSB-) (NP (NNS:[73..83] Mechanisms)) (PP (IN:[84..86] of) (NP (NP (JJ:[87..97] protective) (NN:[98..104] action)) (PP (IN:[105..107] of) (NP (NP (NN:[108..113] radix) (NNP:[114..121] Salviae) (NNP:[122..135] miltiorrhizae)) (NP (-LRB-:[136..137] -LRB-) (NN:[137..140] RSM) (-RRB-:[140..141] -RRB-)))))) (PP (IN:[142..149] against) (NP (JJ:[151..163] experimental) (JJ:[164..171] hepatic) (NN:[172..178] injury))) (PP-LOC (IN:[179..181] in) (NP (NNS:[182..186] rats))) (-RRB-:[186..187] -RSB-))) ;section 2 Span:191..211 ;[Article in Chinese] (SEC (FRAG (-LRB-:[191..192] -LSB-) (NN:[192..199] Article) (IN:[200..202] in) (JJ:[203..210] Chinese) (.:[210..211] -RSB-))) ;section 3 Span:215..264 ;Deng H, Ma X, Xu R, Chen X, Zhao Y, Yin L, Han D. (SEC (FRAG (NNP:[215..219] Deng) (NNP:[220..222] H,) (NNP:[223..225] Ma) (NNP:[226..227] X) (,:[227..228] ,) (NNP:[229..231] Xu) (NNP:[232..233] R) (,:[233..234] ,) (NNP:[235..239] Chen) (NNP:[240..241] X) (,:[241..242] ,) (NNP:[243..247] Zhao) (NNP:[248..249] Y) (,:[249..250] ,) (NNP:[251..254] Yin) (NNP:[255..257] L,) (NNP:[258..261] Han) (NNP:[262..264] D.))) ;section 4 Span:268..300 ;Shanxi Medical College, Taiyuan. (SEC (FRAG (NNP:[268..274] Shanxi) (NNP:[275..282] Medical) (NNP:[283..290] College) (,:[290..291] ,) (NNP:[292..299] Taiyuan) (.:[299..300] .))) ;sentence 5 Span:304..667 ;The results indicated that RSM could significantly inhibit the lipid ;peroxidation of normal livers and cultured hepatocytes of rats, induce liver ;microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, ;urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ;ultrastructural damage of cultured hepatocytes induced by CCl4. ;[331..334]:substance:"RSM" ;[367..372]:substance:"lipid" ;[463..478]:cyp450:"cytochrome P450" ;[504..517]:substance:"nucleic acids" ;[519..527]:substance:"proteins" ;[530..534]:substance:"urea" ;[539..553]:substance:"cerolloplasmin" ;[662..666]:substance:"CCl4" (SENT (S (NP-SBJ (DT:[304..307] The) (NNS:[308..315] results)) (VP (VBD:[316..325] indicated) (SBAR (IN:[326..330] that) (S (NP-SBJ (NN:[331..334] RSM)) (VP (MD:[335..340] could) (VP (VP (ADVP (RB:[341..354] significantly)) (VB:[355..362] inhibit) (NP (NP (DT:[363..366] the) (NN:[367..372] lipid) (NN:[374..386] peroxidation)) (PP (IN:[387..389] of) (NP (NP (NP (JJ:[390..396] normal) (NNS:[397..403] livers)) (CC:[404..407] and) (NP (VBN:[408..416] cultured) (NNS:[417..428] hepatocytes))) (PP (IN:[429..431] of) (NP (NNS:[432..436] rats))))))) (,:[436..437] ,) (VP (VB:[438..444] induce) (NP (NN:[445..450] liver) (JJ:[452..462] microsomal) (NN:[463..473] cytochrome) (NN:[474..478] P450)) (PP-LOC (IN:[479..481] in) (NP (JJ:[482..488] normal) (NNS:[489..493] rats)))) (,:[493..494] ,) (VP (VB:[495..503] increase) (NP (NP (NP (JJ:[504..511] nucleic) (NNS:[512..517] acids)) (,:[517..518] ,) (NP (NNS:[519..527] proteins)) (,:[527..528] ,) (NP (NN:[530..534] urea)) (CC:[535..538] and) (NP (NN:[539..553] cerolloplasmin))) (PP (IN:[554..556] of) (NP (NP (VBN:[557..564] damaged) (VBN:[565..573] cultured) (NNS:[574..585] hepatocytes)) (PP (IN:[586..588] of) (NP (NNS:[589..593] rats))))))) (,:[593..594] ,) (VP (VB:[595..602] relieve) (NP (NP (JJ:[604..619] ultrastructural) (NN:[620..626] damage)) (PP (IN:[627..629] of) (NP (VBN:[630..638] cultured) (NNS:[639..650] hepatocytes))) (VP (VBN:[651..658] induced) (NP (-NONE-:[658..658] *)) (PP (IN:[659..661] by) (NP-LGS (NN:[662..666] CCl4))))))))))) (.:[666..667] .))) ;sentence 6 Span:668..787 ;The pharmacological actions mentioned above should be considered as ;important mechanisms of RSM against liver injury. ;[762..765]:substance:"RSM" (SENT (S (NP-SBJ-1 (NP (DT:[668..671] The) (JJ:[673..688] pharmacological) (NNS:[689..696] actions)) (VP (VBN:[697..706] mentioned) (NP (-NONE-:[706..706] *)) (ADVP (RB:[707..712] above)))) (VP (MD:[713..719] should) (VP (VB:[720..722] be) (VP (VBN:[723..733] considered) (NP-1 (-NONE-:[733..733] *)) (PP (IN:[734..736] as) (NP (NP (JJ:[737..746] important) (NNS:[748..758] mechanisms)) (PP (IN:[759..761] of) (NP (NN:[762..765] RSM))) (PP (IN:[766..773] against) (NP (NN:[774..779] liver) (NN:[780..786] injury)))))))) (.:[786..787] .))) ;section 7 Span:791..835 ;PMID: 1384545 [PubMed - indexed for MEDLINE] (SEC (FRAG (NNP:[791..795] PMID) (::[795..796] :) (CD:[797..804] 1384545) (NN:[805..806] -LSB-) (NNP:[806..812] PubMed) (::[813..814] -) (NN:[815..822] indexed) (IN:[823..826] for) (NNP:[827..835] MEDLINE-RSB-)))