Horm Res. 1979;11(4):179-85.  

Subcellular distribution of aromatase in human placenta and ovary.

Thompson EA Jr, Siiteri PK.

The aromatization of androstenedione in human ovarian microsomes is inhibited by
an antibody to porcine hepatic microsomal NADPH-cytochrome c reductase.
Likewise, the antibody inhibits aromatization in mitochondria isolated from
human ovaries and placentae. A given quantity of the antibody produces the same
percent inhibition of aromatization in microsomes and mitochondria of both
ovaries and placentae. These data, in addition to the low specific activity
observed for the mitochondrial aromatase, indicate that aromatization in
mitochondria probably results from microsomal contamination.

PMID: 115774 [PubMed - indexed for MEDLINE]